Method | Strengths | Weaknesses |
---|---|---|
Hypergeometric | Gold standard for overlapping sets | Fails for split sets |
Local extension | Moderate improvement upon split sets | Â |
Diffusion - AUC | Exceptional improvement upon split sets | Considerable performance loss for GO overlap sets Strong correlation with centrality |
Diffusion - AP | Matches hypergeometric for overlapping sets Major improvement upon split sets | Weak correlation with centrality Strong correlation with set size |
RIDDLE | Best for split sets | Minor performance loss for GO overlap sets |