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Figure 3 | Genome Biology

Figure 3

From: The rate of the molecular clock and the cost of gratuitous protein synthesis

Figure 3

Correlation of E. coli mRNA expression with Ka, protein solubility, and the fraction of charged residues. (a) Correlation between expression and the rate of non-synonymous substitutions (Ka; Spearman's r = -0.45, P < 10-10). (b) Correlation between Ka and the rate of synonymous substitutions (Ks; r = 0.66, P < 10-10). (c) Correlation between expression and protein solubility measured in vitro [48] (r = 0.27, P < 10-10). (d) Correlation between expression and the fraction of charged residues (r = 0.28, P < 10-10). The red lines on each panel represent a 200-point moving average.

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