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Figure 9 | Genome Biology

Figure 9

From: Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions

Figure 9

Heat maps showing high overlap in binding among the blastoderm factors. (a, b) Each row shows the percentage of a cohort of 300 single nucleotide position peaks for a factor that are overlapped by 1% FDR regions bound by each of the other factors in turn. (c, d) Each row shows the Genome Structure Correction z scores for the likelihood that the overlap plotted in (a, b) occurs by chance given the proportion of the genome bound by each factor. (a, c) Results for the most highly bound 300 peaks (1-300). (b, d) Results for the second most highly bound cohort of 300 peaks (301-600). Note that the 1% FDR threshold does not lie within ranks 1 to 600 for 17 of the 21 factors shown, and, thus, for these proteins the bulk of the differences observed between the 1-300 and the 301-600 cohorts are not attributable to false positives.

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