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Figure 5 | Genome Biology

Figure 5

From: Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions

Figure 5

Genes that control development are enriched in highly bound regions. The five most enriched Gene Ontology terms [68] in the 1% FDR bound regions for each factor were identified (enrichment measured by a hyper geometric test). The significance of the enrichment (-log(P-value)) of these five terms in non-overlapping cohorts of 200 peaks are shown down to the rank list as far as the 25% FDR cutoff. The most highly bound regions are to the left along the x-axis and the location of 1% FDR threshold is indicated by a black, vertical dotted line. Shown are the results for the (a) BCD 2, (b) DA 2, (c) HRY 2, and (d) RUN 1 antibodies. Dev., development; periph., peripheral; RNA pol, RNA polymerase; txn, transcription.

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Genome Biology

ISSN: 1474-760X

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