Figure 2

Performance of GO term prediction using either the RF guilt-by-profiling (RF; brown) or FL guilt-by-association classifiers (FL). Three types of FL classifiers were compared: FL1 (green), which used only gene characteristics used in the RF classifier that have been recoded as gene pair characteristics; FL2 (red), which used only 'intrinsic' gene-gene relationships; and FL3 (blue), which used both intrinsic and recoded gene-gene characteristics. (a-l) Plots are organized according to GO branch and GO term specificity. FL, functional linkage; GO, Gene Ontology; RF, random forest.