Table 3 Non-aging and non-estrogen-associated probe sets that are differentially expressed in wounds from elderly compared to young subjects
From: Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly
Affy ID | Gene | Gene (description) | Function | q-value* | FC†|
|---|---|---|---|---|---|
Downregulated probe sets (10) | Â | Â | Â | Â | Â |
   205000_at | DDX3Y | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked | Male fertility-associated RNA helicase | 5.9E-13 | -78.6 |
   217521_at | N54942 | Transcribed locus | Unknown | 1.1E-05 | -20.1 |
   213780_at | TCHH | Trichohyalin | Hair follicle/cornified envelope | 1.0E-02 | -13.8 |
   220322_at | IL1F9 | interleukin 1 family, member 9 | Keratinocyte cytokine | 9.7E-04 | -9.9 |
   218454_at | FLJ22662 | hypothetical protein FLJ22662 | Unknown | 1.2E-03 | -9.9 |
   218150_at | ARL5A | ADP-ribosylation factor-like 5A | Developmentally regulated nuclear protein | 1.8E-03 | -9.0 |
   205001_s_at | DDX3Y | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked | Male fertility-associated RNA helicase | 1.1E-05 | -8.6 |
   214131_at | CYorf15B | chromosome Y open reading frame 15B | X-degenerate gene | 1.1E-03 | -8.1 |
   203180_at | ALDH1A3 | Aldehyde dehydrogenase 1 family, member A3 | Detoxification of aldehydes | 7.8E-03 | -8.0 |
   207602_at | TMPRSS11D | transmembrane protease, serine 11D | Psoriasis-associated serine protease | 2.3E-04 | -7.9 |
Upregulated probe sets (2) | Â | Â | Â | Â | Â |
   213369_at | PCDH21 | protocadherin 21 | Adhesion | 1.3E-05 | 11.9 |
   221501_x_at | LOC339047 | hypothetical protein LOC339047 | Unknown | 9.8E-05 | 9.3 |