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Figure 4 | Genome Biology

Figure 4

From: Chlamydia trachomatisdiversity viewed as a tissue-specific coevolutionary arms race

Figure 4

C. trachomatis's evolutionary history. The global phylogenetic tree (NJ, K2P model) is based on about 50,000 bp/taxa. Bootstrap values (1,000 replicates) are shown next to the branch nodes. Ocular, epithelial-genital and LGV strains are represented within yellow, pink and blue boxes, respectively. Charts show the loci contributing to taxa segregation for the assigned tree branches, where the most prominent ones (genetic variability >4%) are highlighted with the corresponding color. Within these highlighted loci, the ones revealing polymorphism (defined as ≥10 SNPs, or >50% amino acid changes when <10 SNPs) among strains infecting the same organ (eyes or lymph nodes), may be involved in pathogenesis (marked with asterisks). Loci without polymorphism within strains infecting the same organ likely reveal the final stages of adaptive evolution (underlined).

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