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Table 2 Sixteen total gene functional groups identified by the Functional Classification Tool

From: The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists

Gene functional group no.

Associated biology

Group enrichment score

1

Chemokine/cytokine

3.37

2

Transcription regulation

2.89

3

Signal transduction/membrane receptors

2.68

4

Kinase activity

2.54

5

DNA damage/repair

2.23

6

Iron binding

2.05

7

RNA processing/splicing factors

1.81

8

Organic acid transport

1.71

9

Cation/ion transport

1.69

10

DNA metabolism/chromosome organization

1.53

11

Cellular macromolecule catabolism

1.41

12

Metalloprotease

1.34

13

Macrotubule

1.24

14

Protein localization/fusion

1.17

15

Amine metabolism

1.1

16

RAS small GTPase

1.03

  1. The genes of demo list 2 were analyzed by the Functional Classification Tool. The major biology terms associated with each group are manually summarized based on gene-term enrichment buttons provided for each functional group.