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Figure 2 | Genome Biology

Figure 2

From: Comparative genomic analysis of the Tribolium immune system

Figure 2

Expansion of the clip-domain family of SPs and SPHs in the T. castaneum genome. The catalytic and proteinase-like domains in the 49 Tribolium sequences are compared with those in 7 Drosophila (Dm), 3 Anopheles (Ag), 3 Holotrichia (Hd), 1 Tenebrio (Tm), 1 Bombyx (Bm) and 3 Manduca (Ms) SP-related proteins. The tree is divided to four clades (A to D). While clade A contains SPHs (yellow) only, the other three are mainly SPs (green). Region D, split into two parts, is intact when all the group D clip-domain proteins from Drosophila and Anopheles are included in the analysis (data not shown). Pink arrowheads at nodes indicate bootstrap values greater than 800 from 1,000 trials. The putative ortholog pairs are connected with green bars. Other than the shown ones (shaded blue, excluding SP126), there are four clusters of clip-domain SP/SPH genes in the genome: (SP)H1 through H6, (S)P7 through P10, H28 and H29, P135 through P139. Some of them (P9, P135 and P139) have no clip domain and, thus, are not shown in the figure.

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