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Figure 6 | Genome Biology

Figure 6

From: Whole-genome analysis of mRNA decay in Plasmodium falciparumreveals a global lengthening of mRNA half-life during the intra-erythrocytic development cycle

Figure 6

K-means clusters of the half-life data for each stage. Genes were clustered into 10 k-means clusters using the log2 transformed half-life (t1/2; minutes) in each stage. The average half-life was used for genes represented by more than one oligo (see Materials and methods). In the plot to the right of each k-means cluster, the average decay profile for each group is displayed (red line) with the average decay profile for the entire dataset (gray line filled down). The x-axis represents the four stages progressing through the life cycle from rings to late schizonts. The y-axis represents half-life from 0 to 100 min. Δt1/2 represents the average half-life difference between the late schizont stage and the ring stage for that group (late schizont half-life - ring half-life). On the right are the top two most significant Gene Ontology terms for each k-means cluster (GoStat was used for this analysis).

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