Skip to main content

Table 2 List of genes identified by MGK as important for growth in the absence of aromatic amino acids

From: Monitoring of gene knockouts: genome-wide profiling of conditionally essential genes

Mutant library used

Genes

Defined

trpAa (28.1)

pheAa (26.1)

epda (23.8)

trpEa (22.8)

aroEa (20.1)

 

tyrAa (17.5)

aroCa (14.8)

trpBa (13.9)

aroAa (13.3)

aroBa (11.9)

 

tyrBa (12.2)

trpDa (7.4)

ygcL (6.6)

rcsF (6.3)

yddK (5.7)

 

ygaF (5.4)

ynaJ (5.3)

pdxAa (5.2)

wzc (5.0)

surA (4.9)

 

rpea (4.8)

ygdDa (4.7)

aroF (4.1)

yadN (4.0)

uvrY (4.0)

 

yeeA (4.0)

ydhH (3.9)

yfhD (3.9)

yadK (3.8)

ompX (3.6)

 

aroDa (3.5)

yfhM (3.5)

yedV (3.4)

ybeL (3.4)

trpCa (3.3)

 

wcaA (3.3)

ydhX (3.2)

   

Random

tyrBa (15.9)

epda (13.3)

trpAa (10.8)

aroEa (10.4)

tyrAa (7.8)

 

trpBa (3.9)

hepA (3.5)

tktAa (3.2)

  
  1. Values in parentheses are intensity ratios (normalized reference intensity value/normalized selection intensity value), and are the average of two independent, inversely labeled experiments. All mutants were individually tested. aMutants that exhibited a growth defect in the absence of aromatic amino acids. MGK, Monitoring of Gene Knockouts.