cis-Decoder discovers constellations of conserved DNA sequences shared among tissue-specific enhancers

Table 2 cis-Decoder libraries

cis-Decoder tag libraries	cDTs	Enhancers	CSBs/Total bp
Mammalian/vertebrate
Neural specific	336	14	286/4,162
Mesodermal specific	258	21	289/3,749
Common	137	35	575/7,911
Neural enriched*	60	35	575/7,911
Mesodermal enriched*	55	35	575/7,911
*Drosophila*
Neural specific	444	36	601/8,002
Segmental specific	284	38	513/6,608
Mesodermal specific	169	25	398/5,469
Neural and segmental	451	75	1,114/14,610
Neural/segmental enriched*	277	100	1,511/20,085
Mesodermal enriched*	104	63	1,511/20,085
Common	993	100	1,511/20,085
*Drosophila* /mammalian/vertebrate
Neural specific	873	50	887/12,164
Mesodermal specific	445	46	687/9,218

* cDTs have a ≥75% correspondence to a specific library but are also present at a low frequency in unrelated enhancers.

ISSN: 1474-760X