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Figure 2 | Genome Biology

Figure 2

From: Towards the uniform distribution of null P values on Affymetrix microarrays

Figure 2

The performance of test statistics in ranking the Latin Square data. (a) ROC curves for Latin Square experiments 8 versus 9. (b,c) The number of true positives captured for all 14 2× Latin Square experiments at a threshold that also captured four false positives (dashed line in panel a) in the absence (panel b) and presence (panel c) of background correction and quantile-quantile normalization. B refers to the 'shrinkage factor' in Equation 3 (see text). For this and the following figures in the report, data were summarized with RMA before application of the test statistic. RMA, Robust Multichip Average; ROC, receiver operating characteristic.

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