GOTax: investigating biological processes and biochemical activities along the taxonomic tree

Table 1 Comparison of query capabilities

	Proteins	Pfam	SMART	GO	Taxonomy	Semantic similarity	Functional similarity
GOTaxExplorer	b,f,c	b,f,c	b,f,c	b,f,c	b,f,c	b,f,-	b,f,-
UniProt	b,f,c	b,f,c	b,f,c	b,f,c	b,f,c	-,-,-	-,-,-
Pfam	b,f,-	b,f,-	-,f,-	-,f,-	b,f,-	-,-,-	-,-,-
SMART	b,f,-	-,f,-	b,f,-	b,f,-	b,f,-	-,-,-	-,-,-
PANTHER*	b,f,-	-,-,-	-,-,-	b,f,c	b,f,c	-,-,-	-,-,-
InterPro	b,f,c	b,f,c	b,f,c	b,f,c	b,f,c	-,-,-	-,-,-
BioDW	b,f,-	-,-,-	-,-,-	b,f,-	-,-,-	b,f,-	-,-,-
GOGraph	-,-,-	-,-,-	-,-,-	-,-,-	-,-,-	b,-,-	b,-,-
DynGO	b,f,-	-,-,-	-,-,-	b,f,-	-,-,-	-,-,-	b,-,-
GFSST^†	b,f,-	-,-,-	-,-,-	b,f,-	-,-,-	-,-,-	b,-,-

*PANTHER provides data for only seven different species. ^†GFFST provides data for only human and mouse. The table shows which information is accessible via the corresponding databases or tools. The entries in each cell stand for (in this order): b, search by; f, search for; c, may be combined with other types. Hyphens "-" indicate a lack of the corresponding functionality.

ISSN: 1474-760X