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Figure 1 | Genome Biology

Figure 1

From: Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase

Figure 1

Clustering of consensus motifs in S. cerevisiae CDK targets. (a) Schematics of characterized S. cerevisiae CDK targets. Blue and green symbols indicate matches to the strong and weak CDK consensus, respectively. The thick black bar below indicates the characterized cy motif in Orc6. The double lines above indicate characterized nuclear localization signals. (b) Sequence of the amino-terminus of Cdc6. Blue and green boxes indicate matches to the strong and weak CDK consensus, respectively. Bold letters indicate the region with the maximal scoring cluster according to S BN . We suggest that this region may be regarded as a regulatory module (see text for details). Thick bars below the sequence indicate matches to the 'cy' motif and thin double lines above the sequence indicate characterized nuclear localization signals. aa, amino acid; CDK, cyclin-dependent kinase.

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