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Table 4 Gene ontologies for up-regulated processes in BCs versus leukocytes

From: GeneChip analysis of human embryonic stem cell differentiation into hemangioblasts: an in silicodissection of mixed phenotypes

Gene category

List hits

EASE score

Development (developmental)

178

6.39E-09

Morphogenesis (developmental)

116

1.98E-08

Organogenesis (developmental)

105

5.04E-08

Cellular process

482

6.48E-08

Cell communication

257

4.78E-07

Cell adhesion

68

4.05E-06

Skeletal development (developmental)

25

4.44E-06

Cell-cell signaling

64

4.86E-06

Ion transport

62

8.10E-05

Circulation

20

9.47E-05

Metal ion transport

38

2.53E-04

Cartilage condensation

6

3.56E-04

Cation transport

46

5.97E-04

G-protein coupled receptor protein signaling pathway

61

8.03E-04

Regulation of blood pressure

9

9.06E-04

Neurogenesis (neuronal)

46

1.17E-03

Second-messenger-mediated signaling

19

1.32E-03

Cell surface receptor linked signal transduction

93

1.52E-03

Bone remodeling

9

2.01E-03

Ossification

9

2.01E-03

Cell homeostasis

15

2.07E-03

Cell ion homeostasis

14

2.27E-03

Ion homeostasis

14

2.27E-03

Transition metal ion transport

9

2.40E-03

Transport

151

2.97E-03

Homeostasis

15

3.10E-03

Transition metal ion homeostasis

7

3.37E-03

Receptor mediated endocytosis

7

4.20E-03

Metal ion homeostasis

11

4.48E-03

Homophilic cell adhesion

15

5.91E-03

Di-, tri-valent inorganic cation homeostasis

10

6.86E-03

Gas transport (erythrocytic)

5

7.51E-03

Oxygen transport (erythrocytic)

5

7.51E-03

Cation homeostasis

12

8.76E-03

Angiogenesis (blood vessel development)

8

1.10E-02

Cyclic-nucleotide-mediated signaling

15

1.13E-02

Transmission of nerve impulse (neurophysiology)

27

1.16E-02

Monovalent inorganic cation transport

28

1.19E-02

Di-, tri-valent inorganic cation transport

14

1.42E-02

Enzyme linked receptor protein signaling pathway

21

1.42E-02

Synaptic transmission (neurophysiology)

26

1.42E-02

Blood vessel development (blood vessel development)

8

1.44E-02

Iron ion homeostasis

5

1.64E-02

Blood coagulation (coagulation)

13

1.80E-02

Tyrosine kinase signaling pathway

15

1.99E-02

Signal transduction

177

2.18E-02

Potassium ion transport

17

2.47E-02

Hemostasis

13

2.77E-02

Pregnancy

8

2.89E-02

Axon guidance (neurophysiology)

6

4.00E-02

  1. When these genes were clustered based on their GO, we identified processes involved in development, nervous system development, blood vessel development and angiogenesis, and erythrocytes.