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Table 6 Category analysis

From: Analysis of cell-based RNAi screens

n

z mean

P

GO category

Description

113

2.5

2 × 10-19

5840 (CC)

Ribosome

81

1.8

4 × 10-9

5829 (CC)

Cytosol

45

2.8

1 × 10-8

0502 (CC)

Proteasome complex

284

1.2

3 × 10-18

6412 (BP)

Protein biosynthesis

96

0.9

1 × 10-5

6397 (BP)

mRNA processing

24

2.2

0.0002

4298 (MF)

Threonine endopeptidase activity

57

0.8

0.0009

8135 (MF)

Translation factor activity, nucleic acid binding

  1. Selected GO categories whose member genes had particularly high z-scores. GO, Gene Ontology; n, number of genes annotated with that category and targeted by the RNAi library; P, P value for the null hypothesis that the mean z-score of the dsRNAs for this category is the same as that of all dsRNAs; RNAi, RNA interference; zmean, mean z-score.
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Genome Biology

ISSN: 1474-760X

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