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Figure 1 | Genome Biology

Figure 1

From: A strategy for extracting and analyzing large-scale quantitative epistatic interaction data

Figure 1

Overview of scoring procedure. (a) Schematic of the procedure used for generating interaction scores from jpeg images of double mutant yeast strain colonies. (b) A representative image of colonies of haploid double mutant yeast strains arising from the mating of one NAT-marked mutant strain to an array of 384 KAN-marked mutant strains, followed by sporulation and a selection process. (c) Median interaction scores as a function of the distance in kilobases between genes. All analysis shown is performed on data from Schuldiner et al. [5].

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