Table 1 Benchmarking scores of ortholog identification methods
From: Benchmarking ortholog identification methods using functional genomics data
Method | Direct conservation of function | Pairwise conservation of function | Overall score | |||
|---|---|---|---|---|---|---|
| Â | Co-expression | Equal InterPro accession number | Conservation of co-expression | Conservation of gene order | Conservation of protein-protein interaction | Â |
Hs-Mm | Â | Â | Â | Â | Â | Â |
BBH | 1.28E+03 (3) | 9.49E+03 (6) | 2.59E+03 (4) | 5.42E+03 (1) | 3.18E+02 (1) | 5.42E+16 (2) |
INP | 1.49E+03 (2) | 1.13E+04 (5) | 2.48E+03 (5) | 4.26E+03 (3) | 3.13E+02 (2) | 5.57E+16 (1) |
KOG | 4.73E+02 (6) | 1.60E+04 (2) | 3.08E+03 (3) | 1.42E+01 (6) | 1.09E+00 (6) | 3.61E+11 (6) |
MCL | 1.66E+03 (1) | 1.20E+04 (4) | 2.41E+03 (6) | 4.56E+03 (2) | 2.34E+02 (3) | 5.10E+16 (3) |
PGT | 1.05E+03 (4) | 1.53E+04 (3) | 4.63E+03 (1) | 1.73E+02 (4) | 1.21E+02 (4) | 1.56E+15 (4) |
Z1H | 9.29E+02 (5) | 1.72E+04 (1) | 3.93E+03 (2) | 3.75E+01 (5) | 3.17E+01 (5) | 7.46E+13 (5) |
Hs-Ce | Â | Â | Â | Â | Â | Â |
BBH | 2.25E+03 (5) | 3.62E+03 (6) | 1.16E+02 (6) | 0.00E+00 (6) | 5.29E+01 (1) | 5.00E+10 (6) |
INP | 3.02E+03 (3) | 5.67E+03 (3) | 2.17E+02 (4) | 2.79E+02 (1) | 7.62E+00 (4) | 7.90E+12 (1) |
KOG | 4.20E+03 (1) | 9.51E+03 (1) | 6.14E+02 (1) | 2.64E+01 (5) | 1.17E+00 (6) | 7.58E+11 (5) |
MCL | 2.50E+03 (4) | 5.01E+03 (4) | 1.76E+02 (5) | 2.95E+01 (4) | 2.94E+01 (2) | 1.91E+12 (2) |
PGT | 3.89E+03 (2) | 9.26E+03 (2) | 3.84E+02 (2) | 5.36E+01 (2) | 1.65E+00 (5) | 1.22E+12 (4) |
Z1H | 2.00E+03 (6) | 4.74E+03 (5) | 2.97E+02 (3) | 4.20E+01 (3) | 1.07E+01 (3) | 1.27E+12 (3) |