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Table 5 Enzymes and transporters in subnetworks

From: Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans

Ethanol versus glucose (26 reactions) Ethanol versus glycerol (33 reactions) Glycerol versus glucose (34 reactions)
6-Phosphofructokinase 1,3-β-Glucan synthase 5'-Phosphoribosylformyl glycinamidine synthetase
Acetyl-CoA hydrolase Acetyl-CoA hydrolase 8-Amino-7-oxononanoate synthase
Aconitate hydratase (mitochondrial) Acetyl-CoA synthase Aldehyde dehydrogenase
Alcohol dehydrogenase Aconitate hydratase (mitochondrial) α,α-Trehalase
Aldehyde dehydrogenase Adenylate kinase α-Glucosidase
α-Glucosidase Alanine-glyoxylate transaminase α-Glucosidase
α-Glucosidase Alcohol dehydrogenase Aspartate-carbamoyltransferase
α-Glucosidase Aldehyde dehydrogenase Aspartate-carbamoyltransferase
Aspartate transaminase (mitochondrial) Aspartate transaminase (mitochondrial) B-ketoacyl-ACP synthase
Aspartate transaminase (mitochondrial) Aspartate transaminase (mitochondrial) Carbamoyl-phophate synthetase
ATP:citrate oxaloacetate-lyase ATP:citrate oxaloacetate-lyase Citrate synthase (mitochondrial)
Carnitine O-acetyltransferase Carnitine O-acetyltransferase Dihydrolipoamide S-acetyltransferase (mitochondrial)
Carnitine O-acetyltransferase (mitochondrial) Carnitine O-acetyltransferase (mitochondrial) Dihydroxy acid dehydratase (mitochondrial)
Carnitine/acyl carnitine carrier Citrate synthase (mitochondrial) Fatty-acyl-CoA synthase
Citrate synthase (mitochondrial) Citrate synthase (mitochondrial) Fatty-acyl-CoA synthase
Formate dehydrogenase Formate dehydrogenase Fructose-bisphosphatase
Fructose-bisphosphatase Fumarate dehydratase (mitochondrial) Glucan 1,3-β-glucosidase (extracellular)
Gluconolactonase (extracellular) Glucose 6-phosphate 1-dehydrogenase Glucose 6-phosphate 1-dehydrogenase
Glucose 6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glycerol 3-phosphate dehydrogenase (FAD dependent)
Glyceraldehyde 3-phosphate dehydrogenase Glycerol 3-phosphate dehydrogenase (FAD dependent) Glycerol dehydrogenase
Isocitrate lyase (glyoxysomal) Glycerol dehydrogenase Glycerol kinase
Glycerol kinase Isocitrate lyase (glyoxysomal) GTP cyclohydrolase I
Mannose-6-phosphate isomerase Malate dehydrogenase (malic enzyme; NADP+) Ketol-acid reductoisomerase (mitochondrial)
Phosphoenolpyruvate carboxykinase Malate synthase (glyoxysomal) Malate dehydrogenase (malic enzyme; NADP+)
Pyruvate kinase Mannitol 2-dehydrogenase (NAD+) Mannitol 2-dehydrogenase (NAD+)
Transketolase Phosphoenolpyruvate carboxykinase Mannitol 2-dehydrogenase (NADP+)
  Phosphoglucomutase Phosphoenolpyruvate carboxykinase
  Phosphogluconate dehydrogenase (decarboxylating) Phosphoribosylamine-glycine ligase
  Phosphorylase Phosphorylase
  Pyruvate kinase Pyruvate dehydrogenase (lipoamide) (mitochondrial)
  Transketolase Pyruvate kinase
  UTP-glucose-1-phosphate uridylyltransferase Ribulokinase
   UTP-glucose-1-phosphate uridylyltransferase
  1. Shown is a list of the enzymes and transporters that participate in the 'small', highly correlated subnetworks for each pair-wise comparison between the three carbon sources investigated. Enzymes common to all reactions are highlighted in bold. Some enzymes appear more than once in the table, which means that they are isoenzymes and are encoded by different genes. CoA, coenzyme A.