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Table 1 BoCaTFBS application in ENCODE projects

From: BoCaTFBS: a boosted cascade learner to refine the binding sites suggested by ChIP-chip experiments

Transcription factor

Methods

TFBSs detected correctly

  

Original

IC

Pair IC

cMyc

PSSM

234

234

261

 

Centroid

232

236

241

 

Berg and von Hippel

245

247

252

 

Consensus

154

219

221

 

Single boosting

347

  
 

BoCaTFBS

444

  

Sp1

PSSM

86

86

90

 

Centroid

93

93

104

 

Berg and von Hippel

107

109

115

 

Consensus

62

68

68

 

Single boosting

119

  
 

BoCaTFBS

123

  

P53

PSSM

16

17

29

 

Centroid

15

15

23

 

Berg and von Hippel

16

19

29

 

Consensus

7

12

17

 

Single boosting

30

  
 

BoCaTFBS

35

  
  1. IC, information content; PSSM, positional specific scoring matrix; TFBS, transcription factor binding site.