The concept of 'cell-omic sensors'. Cell-based detection systems can be combined with arrayed probes to allow multi-parameter analysis. By arraying cells in a monolayer on top of probes (such as antibodies), it would be possible to detect changes in multiple cellular components simultaneously. Components secreted from the cell or expressed on its surface could be detected directly by the probes; detection of intracellular components would require the use of more sophisticated techniques. Information would be collected directly from the underlying probes through detection systems positioned below the probes.