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Table 3 Genes upregulated with term activation

From: Identifying genetic networks underlying myometrial transition to labor

 

Gene symbol

Fold-change at 18 days

Regulation of cell growth

  

Inhibin beta-B

Inhbb

3.1

Inhibin beta-A

Inhba

2.2

Cell death

  

Growth arrest and DNA-damage-inducible 45 γ

Gadd45g

3.2

Baculoviral IAP repeat-containing 1a

Birc1a

2.1

Clusterin

Clu

2.0

Cell junctions

  

Occludin

Ocln

2.8

Gap junction membrane channel protein α1

Cx43

2.8

Desmoplakin

Dsp

2.8

G-protein signaling

  

Lysophosphatidic acid receptor Edg-2

Edg2

2.8

Guanine nucleotide binding protein, γ12

Gng12

2.1

Structural constituent of cytoskeleton

  

Villin 2

Vil2

3.1

Kinesin complex

  

Keratin complex 1, acidic, gene 19

Krt1-19

7.8

Keratin complex 2, basic, gene 7

Krt2-7

4.6

Keratin complex 2, basic, gene 8

Krt2-8

4.6

Keratin complex 1, acidic, gene 18

Krt1-18

4.5

Surfactant associated protein D

Sftpd

3.4

Metabolism and biosynthetic reactions

  

Lipoprotein lipase

Lpl

4.5

Aldehyde dehydrogenase family 1, subfamily A2

Aldh1a2

3.9

Glutathione S-transferase omega 1

Gsto1

3.7

Branched chain aminotransferase 1, cytosolic

Bcat1

3.4

Protein phosphatase 1, regulatory subunit 3C

Ppp1r3c

2.2

Carbonic anhydrase 2

Car2

2.1

Proteolysis and peptidolysis

  

Cytosolic nonspecific dipeptidase

0610010E05Rik

3.2

Transmembrane protease, serine 2

Tmprss2

2.1

Kallikrein 5

Klk5

2.1

Collagen catabolism

  

Peptidase 4

Pep4

2.3

Matrix metalloproteinase 7

Mmp7

2.2

Proteolysis inhibitors

  

Complement component 3

C3

4.3

RIKEN cDNA 1600023A02 gene

1600023A02Rik

2.9

Extracellular proteinase inhibitor

Expi

2.8

Transcriptional regulation

  

Transcription factors

  

Myeloblastosis oncogene

Myb

2.5

Hairy and enhancer of split 1

Hes1

2.3

E74-like factor 3

Elf3

2.1

Androgen regulation

  

Kidney androgen regulated protein

Kap

33.9

Heat shock protein 4

Hspa4

3.1

Alpha fetoprotein

Afp

3.1

Transport

  

FXYD domain-containing ion transport regulator 3

Fxyd3

2.8

Lipocalin 2

Lcn2

2.5

Lactotransferrin

Ltf

2.2

Solute carrier family 16, member 1

Slc16a1

2.1

Fatty acid binding protein 5, epidermal

Fabp5

2.0

  1. Only upregulated genes with a relative fold-change of 2 or more versus non-pregnant mice at 18.5 days gestation and linked to biological categories highlighted by the expression analysis are shown. Full gene lists can be obtained online (see Additional data file 6).
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Genome Biology

ISSN: 1474-760X

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