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Table 4 Cross-classification of interaction and localization - single projections

From: Ulysses - an application for the projection of molecular interactions across species

 

Yeast two-hybrid

Complex purification

Interactions

Yeast

Worm

Fly

Yeast

 

Random

BIND

Random

BIND

Random

BIND

Random

BIND

No co-localization

9,493

3

9,475

21

9,454

42

9,314

182

Co-localization

18,656

102

18,614

144

18,628

130

17,411

1,347

Total

28,149

105

28,089

165

28,082

172

26,725

1,529

Success rate

66.28

97.14

66.27

87.27

66.33

75.58

65.15

88.10

p-value

 

4.3e-09

 

8.67e-08

 

0.0111

 

2e-16

  1. Interactions from model organisms reported in BIND for which both interactors could be mapped to human homologs (HPRD) were evaluated for co-localization. Random interactions generated for HPRD interactors are shown as control datasets.