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Table 1 Properties of human MAP2/Tau family genes

From: The MAP2/Tau family of microtubule-associated proteins

Gene Locus Predicted exons Splice form Number of microtubule-binding repeats Alternatively spliced exons
MAP2 2q34-q35 18 Isoform 1 (MAP2b) 3 +9, +10, +11, -16
    Isoform 2 (MAP2c) 3 -9, -10, -11, -16
    Isoform 3 4 +9, +10, +11, +16
    Isoform 4 (MAP2d) 4 -9, -10, -11, +16
    MAP2a Unknown +8, +9, +10, +11, (16?)
Tau 17q21.1 17 Isoform 1 (HMW-tau) 4 +2, +3, +4A, +6, +10
    Isoform 2 (tau 4R/2N) 4 +2, +3, -4A, -6, +10
    Isoform 3 (tau 4R/0N) 4 -2, -3, -4A, -6, +10
    Isoform 4 (tau 3R/0N) 3 -2, -3, -4A, -6, -10
MAP4 3p21 23 Various isoforms 3-5 Various
  1. Chromosomal localization and sequence information about reviewed alternative splice forms were obtained from LocusLink [75]. Commonly used designations for splice forms are indicated in brackets.