All S. cerevisiae genes | Percentage of total | Selected toxic genes | Percentage of total | |
---|---|---|---|---|
Functional classes (MIPS data) | ||||
Cell cycle_DNA processing | 670 | 11.5 | 75 | 16.5* |
Cell fate | 486 | 8.4 | 66 | 14.5* |
Cell rescue, defense and virulence | 288 | 5.0 | 23 | 5.1 |
Cellular communication/signal transduction mechanism | 59 | 1.0 | 6 | 1.3 |
Cellular transport and transport mechanisms | 525 | 9.0 | 67 | 14.8* |
Classification not yet clear-cut | 112 | 1.9 | 6 | 1.3 |
Control of cellular organization | 207 | 3.6 | 22 | 4.8 |
Energy | 244 | 4.2 | 12 | 2.6 |
Metabolism | 1,061 | 18.3 | 88 | 19.4 |
Protein fate (folding, modification, destination) | 593 | 10.2 | 47 | 10.4 |
Protein synthesis | 377 | 6.5 | 17 | 3.7* |
Regulation of/interaction with cell. Environment | 197 | 3.4 | 29 | 6.4 † |
Transcription | 801 | 13.8 | 88 | 19.4* |
Transport facilitation | 321 | 5.5 | 61 | 13.4* |
Unclassified | 1,706 | 29.4 | 91 | 20.0* |
Cellular localization (MIPS data) | ||||
Extracellular | 54 | 1.4 | 5 | 1.6 |
Cell wall | 38 | 1.0 | 4 | 1.3 |
Golgi | 103 | 2.6 | 8 | 2.5 |
Transport vesicles | 54 | 1.4 | 3 | 0.9 |
Plasma membrane | 171 | 4.4 | 34 | 10.7* |
Nucleus | 1,367 | 34.8 | 130 | 40.8 † |
Cytoplasm | 2,001 | 50.9 | 137 | 42.9* |
Peroxisome | 42 | 1.1 | 3 | 0.9 |
Endosome | 20 | 0.5 | 2 | 0.6 |
Cytoskeleton | 154 | 3.9 | 22 | 6.9 † |
Vacuole | 82 | 2.1 | 8 | 2.5 |
Endoplasmic reticulum | 353 | 9.0 | 27 | 8.5 |
Mitochondria | 562 | 14.3 | 37 | 11.6 |
Viability (MIPS data) | ||||
Essential | 939 | 16.2 | 96 | 21.1 † |
Essential or not | 160 | 2.8 | 20 | 4.4 |
Phylogeny (Génolevures data) | ||||
Conserved | 3,717 | 64.1 | 336 | 74.0* |
Ascomycete-specifics | 1674 | 28.8 | 106 | 23.3* |
Orphan | 412 | 7.1 | 10 | 2.2* |