A first-draft human protein-interaction map

Table 2 The number of interactions, genes, novel genes and disease genes in the complete and core human interaction networks

Network	Interactions	Genes	Novel genes	Disease genes
Complete	71,496	6,231	1,482	448
Core	11,487	3,872	864	292

The complete network consists of all human protein interactions predicted by model organism protein-interaction datasets. The core network consists of all the human interactions predicted by the high-confidence subsets of each interaction network (see Materials and methods). Novel genes are defined as those without GO annotations. Disease genes are defined by the OMIM database [25], available from Ensembl [16].

ISSN: 1474-760X