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Figure 5 | Genome Biology

Figure 5

From: START lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors

Figure 5

The structures of HD-START proteins from plants in comparison to classic nuclear receptors from animals. (a) Plant-specific HD-ZLZ START and HD-ZIP START proteins are transcription factors comprised of an amino-terminal HD DNA-binding domain preceding START, a putative lipid/sterol-binding domain. (b) Nuclear receptors, which are found only in animal genomes, comprise a zinc finger DNA-binding domain of the C4 (two domain) type (zf-C4), and a carboxy-terminal hormone receptor (HR) domain that binds steroid ligands. Members of the nuclear receptor superfamily bind other lipophilic molecules, such as retinoic acid or thyroxine.

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