Transcriptional regulation of protein complexes in yeast

Table 3 Details of the discriminant analysis results for the replication fork complexes

Complex	Gene	ORF	P(da)
Components predicted to be co-regulated
DNA polymerase αI primase complex	POL1	YNL102W	0.95155315
	PRI2	YKL045W	0.92757655
	POL12	YBL035C	0.8740073
	PRI1	YIR008C	0.14922267
DNA polymerase δIII	POL32	YJR043C	0.88528264
	HYS2	YJR006W	0.79712089
	CDC2	YDL102W	0.79079457
DNA polymerase εII	POL2	YNL262W	0.85845235
	DPB2	YPR175W	0.7575824
	DPB3	YBR278W	0.64557167
Exonucleases	RAD27	YKL113C	0.99432872
PCNA	POL30	YBR088C	0.69668482
Replication factor A complex	RFA1	YAR007C	0.98673268
	RFA2	YNL312W	0.87875323
	RFA3	YJL173C	0.73210048
Topoisomerases	TOP1	YOL006C	0.82395424
	TOP2	YNL088W	0.73032433
Components excluded from the predicted regulon group
DNA helicases	ECM32	YER176W	0.23499023
	DNA2	YHR164C	0.05406037
DNA ligases	CDC9	YDL164C	0.03708159
DNA polymerase βIV	POL4	YCR014C	0.03919368
DNA polymerase γ	MIP1	YOR330C	0.03182497
DNA polymerase ζ	REV7	YIL139C	0.05724429
	REV3	YPL167C	0.04090946
Replication factor C complex	RFC4	YOL094C	0.50870756
	RFC5	YBR087W	0.33589936
	RFC3	YNL290W	0.26089619
	RFC2	YJR068W	0.10584985
	RFC1	YOR217W	0.05246123
RNase H1	RNH1	YMR234W	0.02989109

The CYGD names of the subcomplexes or independent genes of the replication fork complexes are listed in column 1. The second and third columns list, respectively, the common gene name and ORF identifier. The posterior probability P(da), computed by the discriminant analysis, with which the listed gene/ORF was assigned to the putative regulon is listed in column 4. All the components predicted to be co-regulated (probability > 0.5 for most of the genes) are listed in the top part of the table, while those excluded from the predicted regulon group are listed in the lower part of the table. The two genes whose assignment is different from those of other related components of the subcomplex are marked in bold.

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