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Table 1 Total number of Mycobacterium tuberculosis genes with linkages based on the Operon method, employing orientation and a nucleotide distance threshold

From: Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach

Threshold (bp)

Predicted operon groups

Genes with links

Functional linkages

0

542

1279

2034

25

792

2071

4442

50

879

2420

5890

75

919

2665

7026

100

933

2870

8468

  1. Column 1 (distance threshold) indicates the intergenic distance, in base pairs, of less than or equal to the indicated value. Notice that at the 0 bp threshold we have links connecting over 25% of the M. tuberculosis genes. As we increase the distance threshold from 0 bp to 100 bp we approach almost 75% of the genes having one or more links to other M. tuberculosis genes.