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Table 1 Chromosomal regions implicated in panic disorder, phobias and anxiety traits

From: Untangling genetic networks of panic, phobia, fear and anxiety

Phenotype

1q

3q

4q21

4q34

7p

8q

9q

10q

11p

12q

13q

14p

22q

Reference

Panic disorder (PD)

+++

+

  

+

++

++++

  

+

++++

+

++++

[13, 15, 16, 19]

 

+

+

 

+

++

    

++*

   

[11, 17]

 

++

        

++

   

[15, 16]

Agoraphobia (AG)

-

++

+

     

++

    

[13]

  

++++*

           

[13]

PD + AG

        

+

  

+

 

[13]

Specific Phobia

+

++

 

+

 

++

 

+

+

  

+++

 

[14]

  

+++*

           

[14]

PD + anxiety

+

 

+

   

++

++

 

+

   

[17, 19]

Neuroticism

++++

  

++++

++++

    

++++

++++

  

[12]

Mouse QTL†

++++

        

++++

 

++++

+++

[17, 27]

  1. *One family. †Human equivalents of mouse QTLs. The number of + signs indicates the approximate relative significance of the linkage.