Category | Term | Gene count in A549 set of 223 | Gene count in U118 set of 256 | Gene count in entire set of 5,682 | p-value A549 set | p-value U118 set |
---|---|---|---|---|---|---|
GO term annotation (0.95 terms expected, found 46) | ||||||
Biological process | Alcohol metabolism | 10 | 15 | 110 | 1.07E-02 | 1.06E-04 |
Biological process | Aromatic compound metabolism | 7 | 6 | 23 | 1.87E-05 | 4.16E-04 |
Biological process | Biosynthesis | 31 | 27 | 330 | 3.88E-06 | 1.69E-03 |
Biological process | Cell cycle | 31 | 33 | 327 | 3.20E-06 | 8.11E-06 |
Biological process | Cell proliferation | 36 | 39 | 535 | 7.98E-04 | 1.53E-03 |
Biological process | Cytokinesis | 8 | 6 | 39 | 1.06E-04 | 7.36E-03 |
Biological process | DNA metabolism | 16 | 12 | 120 | 1.52E-05 | 7.46E-03 |
Biological process | DNA replication | 13 | 10 | 81 | 1.30E-05 | 3.22E-03 |
Biological process | G1/S transition of mitotic cell cycle | 5 | 7 | 39 | 1.73E-02 | 1.55E-03 |
Biological process | Metabolism | 108 | 134 | 2278 | 6.12E-03 | 3.34E-05 |
Biological process | Mitotic cell cycle | 9 | 10 | 54 | 2.14E-04 | 1.20E-04 |
Biological process | Nucleotide biosynthesis | 10 | 5 | 31 | 1.52E-07 | 1.16E-02 |
Biological process | Regulation of CDK activity | 5 | 6 | 23 | 1.68E-03 | 4.16E-04 |
Biological process | Tricarboxylic acid cycle | 3 | 5 | 12 | 1.01E-02 | 1.09E-04 |
Molecular function | ATP binding activity | 29 | 33 | 425 | 2.18E-03 | 1.28E-03 |
Molecular function | Cyclin-dependent protein kinase activity | 6 | 8 | 25 | 3.23E-04 | 8.44E-06 |
Molecular function | Enzyme activity | 90 | 109 | 1466 | 8.76E-07 | 1.70E-09 |
Molecular function | Ligase activity | 14 | 11 | 72 | 5.40E-07 | 3.28E-04 |
Molecular function | Lyase activity | 8 | 8 | 75 | 8.69E-03 | 1.88E-02 |
Molecular function | Nucleotide binding activity | 40 | 42 | 564 | 1.28E-04 | 6.40E-04 |
MeSH term association (2.2 terms expected, found 37) | ||||||
Anatomy | Intracellular membranes | 21 | 30 | 344 | 2.79E-02 | 3.20E-04 |
Anatomy | Mitochondria | 38 | 52 | 607 | 2.17E-03 | 2.46E-06 |
Biological sciences | Active transport, Cell nucleus | 23 | 23 | 329 | 4.68E-03 | 2.26E-02 |
Biological sciences | Cell cycle | 62 | 66 | 980 | 4.19E-05 | 2.82E-04 |
Biological sciences | DNA replication | 30 | 33 | 440 | 1.84E-03 | 2.28E-03 |
Biological sciences | Genes, lethal | 17 | 16 | 211 | 3.61E-03 | 2.78E-02 |
Biological sciences | Mitosis | 28 | 37 | 484 | 2.30E-02 | 8.57E-04 |
Biological sciences | Mutagenesis | 52 | 55 | 940 | 4.84E-03 | 2.07E-02 |
Biological sciences | Oxidative stress | 30 | 36 | 454 | 2.98E-03 | 5.13E-04 |
Biological sciences | S phase | 21 | 22 | 272 | 2.12E-03 | 5.18E-03 |
Chemicals and drugs | Acetyl coenzyme A | 4 | 4 | 24 | 1.32E-02 | 2.10E-02 |
Chemicals and drugs | Adenosinetriphosphatase | 30 | 36 | 416 | 7.50E-04 | 9.02E-05 |
Chemicals and drugs | Antineoplastic agents | 49 | 55 | 897 | 8.09E-03 | 8.39E-03 |
Chemicals and drugs | Cyclin B | 10 | 15 | 101 | 5.96E-03 | 3.87E-05 |
Chemicals and drugs | Cyclin-dependent kinases | 21 | 30 | 336 | 2.22E-02 | 2.12E-04 |
Chemicals and drugs | Cysteine endopeptidases | 26 | 29 | 418 | 1.21E-02 | 1.22E-02 |
Chemicals and drugs | Multienzyme complexes | 35 | 35 | 512 | 7.14E-04 | 7.58E-03 |
Chemicals and drugs | Phosphoglucomutase | 5 | 6 | 30 | 5.68E-03 | 1.88E-03 |
Chemicals and drugs | RNA nucleotidyltransferases | 5 | 5 | 33 | 8.60E-03 | 1.51E-02 |
Diseases | Carcinoma in situ | 6 | 7 | 55 | 1.99E-02 | 1.11E-02 |