Multi-level response of the yeast genome to glucose

Table 1 DNA sequences bound by glucose-regulated transcription factors

Transcription factor	Binding site*	Main function	References
Cat8	YCCRTYSRNCCG	Activator of gluconeogenic genes	[27]
Sip4	YCCRTYSRNCCG	Activator of gluconeogenic genes	[28]
Mig1/Mig2	T(C/G)(C/T)GGGG	Repressors of SUC, MAL and GAL genes	[29]
Gcr1	CTTCC	Activator of glycolytic genes	[30]
Rgt1	CGGANNA	Regulator of HXT gene expression	[31]
Nrg1/Nrg2	Not determined	Repressors of SUC, GAL and FLO11 genes, interact with Snf1	[32–34]
Azf1	AAGAAAAA	Induction of CLN3 gene expression	[23]
Msn2/Msn4	CCCCT	Induction of STRE-regulated genes	[20]
Gis1	T(T/A)AGGGAT	Activator of post-diauxic shift (PDS) genes	[21]
Pop2-Ccr4-Not	Not determined	Global transcriptional regulator of growth-, metabolism- and stationary phase related proteins	[35]

*Within DNA sequences, Y denotes a pyrimidine and R a purine. Abbreviation: STRE, stress-response element.

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