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Table 2 The complete list of bHLH genes from Homo sapiens

From: Phylogenetic analysis of the human basic helix-loop-helix proteins

Sequence identification Gene name Family Mouse ortholog(s) Contigs Chromosome localization
P50553 Hash1 Achaete-Scute a Mash1 NT_009439.3 12q22-q23
Q99929 Hash2 Achaete-Scute a Mash2 NT_009368.3 11p15.5
N024228 Hash3a * Achaete-Scute b Mash3 NT_024228.3 11p15.3
N004680 Hash3b * Achaete-Scute b ? NT_004680.3 1q31-q32
N009720 Hash3c * Achaete-Scute b ? NT_009720.3 12q23-q24
P15173 Myf4 MyoD Myogenin NT_004662.3 1q31-41
P23409 Myf6 MyoD Myf6 NT_024473.2 12q21
P15172 Myf3 MyoD MyoD NT_009307.3 11p15.4
P13349 Myf5 MyoD Myf5 NT_024473.2 12q21
N011269 E2A * E12/E47 E2A NT_011269.3 19p13.3
Q99081 TF12 E12/E47 TF12 NT_010289.3 15q21
P15884 TCF4 E12/E47 TCF4 NT_011059.5 18q21.1
P15884 D TCF4b * E12/E47 TCF4 NT_029427.1 12
P15923 TCF3 E12/E47 ? NT_011269.3 19p13.3
N008413   E12/E47 ? NT_008413.3 9p22-q22
Q92858 Hath1 Atonal Math1 ? 4q22
N029388 Hath5 * Atonal Math5 NT_029388.3 10q21-q26
N007816 Mist1 * Mist Mist1 NT_007816.3 7q21-q31
N011512 Oligo1 * Oligo Oligo 1 NT_011512.3 21q21-q22
Q9NZ14 Oligo2 * Oligo Oligo 2 ? ?
N025741 Oligo3 * Oligo Oligo 3 NT_025741.3 6q22-q24
N030199 Beta3a * Beta3 Beta3 NT_030199.1 8q21
N011333 Beta3b * Beta3 Q9H494 NT_011333.4 20p11-q13
Q9H2A3 Neurogenin2 Neurogenin Math4a NT_022859.3 4
N024089 Hath4b Neurogenin Math4b NT_024089.3 10q21.3
Q92886 NDF3 Neurogenin NDF3 NT_007091.3 5q23-Q31
N009563 Hath3 * NeuroD Math3 NT_009563.3 12q13-q14
N007819 Hath2 * NeuroD Math2 NT_007819.6 7p14-p15
Q15784 NDF2 NeuroD NDF2 NT_010685.3 17q12
Q13562 NDF1 NeuroD NDF1 NT_005272.3 2q32
N010356a Mesp1 * Mesp ? NT_010356.6 15q25-q26
N010356b Mesp2 * Mesp ? NT_010356.6 15q25-q26
N010356c Mesp3 * Mesp ? NT_010356.6 15q25-q26
N015926 Mesp4 * Mesp pMeso1 NT_015926.3 2p24
N015805 Hath6 * Net Math6 NT_015805.6 2p11-q24
N005204a MyoR1 * MyoR Pod1 NT_005204.6 2p21-p25
N008253 MyoR2 * MyoR MyoR NT_008253.3 8q13
N005204b MyoR3 * MyoR ? NT_005204.6 2p21-p25
N008166 MyoR4 * MyoR ? NT_008166.3 8q13-q22
Q9HC25 P48 PTFa PTF1 NT_008895.6 10p12-q22
N007918 PTFb * PTFb ? NT_007918.6 7p15-p21
O96004 ehand Hand eHand NT_026280.4 5q33
O95300 dHand Hand dHand NT_006257.3 4q31-q33
Q15672 twist Twist Twist NT_007918.3 7p21
N011493 paraxis * Paraxis paraxis NT_011493.3 20
Q02577 NSCL-2 NSCL Hen2 NT_021883.3 1p11-p12
Q02575 NSCL-1 NSCL Hen1 NT_004406.3 1q22
Q16559 Tal2 SCL Tal2 NT_008470.3 9q31
P17542 Tal1 SCL Tal1 NT_004701.3 1p32
P12980 Lyl SCL Lyl1+Lyl2 NT_011247.3 19p13.2
Q01664 AP4 AP4 AP4 NT_015360.3 19p13
Q99583 Mnt Mnt Mnt NT_010692.3 17p13.3
Q14582 Mad4 Mad Mad4 NT_022865.3 4p16.3
Q9H7H9 Mad4b * Mad ? NT_022865.3 4p16.3
P50539 Mxi1 Mad Mxi1 NT_024048.3 10q25
Q05195 Mad1 Mad Mad1 NT_005420.3 2p12-p13
AAH00745 Mad3 Mad Mad3 ? ?
P25912 Max Max Max NT_025892.3 14q23
P04198 N-Myc Myc N-Myc NT_026240.1 2p24.1
P01106 C-Myc Myc C-Myc NT_008012.3 8q24
P12524 L-Myc1 Myc L-Myc NT_004893.3 1p34
P12525 L-Myc2 Myc ? NT_011762.3 Xq22-q23
N011572 L-Myc3 * Myc ? NT_011572.3 Xq27
O43792 SRC1 SRC SRC1 NT_005204.3 2p22-p25
Q15596 SRC2 SRC SRC2 NT_023676.3 8p22-q21
Q9Y6Q9 SRC3 SRC SRC3 NT_011371.3 20q12
O75030 MITF MITF MITF NT_005510.3 3p12-p14
P19532 TFE3 MITF TFE3 NT_011611.3 Xp11
P19484 TFEB MITF TFEB NT_023409.3 6p21
O14948 TFEC1 MITF TFEC NT_026338.1 7
N009714 TFEC2 * MITF TFEC NT_009714.3 12p11-q14
P36956 SREBP1 SREBP SREBP1 NT_010657.3 17p11.2
Q12772 SREBP2 SREBP SREBP2 NT_011520.3 22q13
P22415 USF1 USF USF1 NT_026219.3 1q22-q23
Q15853 USF2 USF USF2 NT_011294.3 19q13
N009711 USF2b * USF USF2 NT_009711.6 12
Q9NP71 MLXa MLX MLX NT_023557.3 7q11
Q9HAP2 Mondoa MLX ? ? 12q21
Q9UH92 TF4a * TF4 TF4 NT_010771.3 17q21.1
N005106 TF4b * TF4 ? NT_005106.6 2p24-q36
N005420 Figa Figa Figa NT_005420.3 2p13-p24
O00327 Bmal1 Bmal Bmal1 NT_017854.3 11p15
Q9NYQ5 Bmal2 Bmal ? NT_009622.3 12p11-p12
P27540 ARNT1 ARNT ARNT1 NT_004811.3 1q21
Q9HBZ2 ARNT2 ARNT ARNT2 NT_004811.6 1q21
O15516 clock1 Clock clock NT_029271.2 4q12
Q99743 NPAS2 Clock NPAS2 NT_022171.6 2q13
Q16665 Hif1a HIF Hif1a ? 14q21-q24
Q99814 EPAS1 HIF EPAS1 NT_029237.2 2p21-p16
O95262 Hif3a HIF Hif3a NT_011166.6 19q13
Q99742 NPAS1 HIF/Sim/Trh NPAS1 NT_011166.3 19q13
P81133 Sim1 Sim Sim1 NT_019424.3 6q16-q21
Q14190 Sim2 Sim Sim2 NT_011512.3 21q22.13
Q9H323 NPAS3 Trh NPAS3 NT_010164.3 14q12-13
Q13804 AHR1 AHR AHR NT_007755.4 7p15
N016866 AHR2 * AHR ? NT_016866.3 5p15
Q9HAZ3 AHR3 * AHR ? NT_016866.3 5p15
N030106 AHR4 * AHR ? NT_030106.1 11q12-q13
Q9Y5J3 Herp2 Hey Hey1 NT_023700.5 8q21
Q9UBP5 Herp1 Hey Herp1 ? ?
Q9NQ87 HEYL Hey ? NT_004893.5 1p34.3
Q9NQ87D HEYLb * Hey ? NT_004893.5 1p34.3
N029966 Hey4 * Hey ? NT_029966.1 4
O14503 Dec1 E(spl) Dec1 NT_005927.3 3p24-p26
BAB21502 Dec2 E(spl) Dec2 NT_009471.3 12p11-p12
N029854 Hes5 * E(spl) Hes5 NT_029854.1 1p36
Q9BYEO Hes7 E(spl) Hes7 NT_010841.2 17p12-p13
N019265 Hes3 * E(spl) Hes3+BAA9469 NT_019265.6 1p36
Q9P2S3 Hes6 * E(spl) Hes6 NT_005139.6 2q36-q37
Q9Y543 Hes2 E(spl) Hes2 NT_019265.6 1p36
Q9BYW0 Cha E(spl) ? NT_011333.4 20q11-q13
Q14469 Hes1 Hairy Hes1 NT_005571.3 3q28-q29
Q9HCC6 Hes4 Hairy ? NT_025635.5 1p36
P41134 Id1 Emc Id1 NT_028392.4 20q11
N00599 Id2 Emc ? NT_005999.3 3p21-q13
Q02363 Id2 Emc Id2 NT_022194.3 2p25
Q02535 Id3 Emc Id3 NT_004359.6 1p36
P47928 Id4 Emc Id4 NT_027049.3 6p21-p22
Q9UH73 EBF1 Coe Coe1 NT_007006.4 5q34
Q9BQW3 Coe2 * Coe ? NT_023666.3 8p21-p22
Q9H4W6 EBF3 Coe ? NT_008818.6 10q25-q26
Q9NUB6 Coe4 * Coe ? ? 20p11-p13
N010809 ? Orphan ? NT_010809.6 17p13.3
Q9NX45 ? Orphan ? NT_030131.1 13q12-q14
Q9H8R3 ? Orphan ? NT_010194.6 15q14-q22
  1. Human sequences are identified using their accession number from Swissprot, Trembl, Smart or NCBI genome project sequences. In the latest case, the accession number is that of the contig which includes the bHLH gene. This accession number NT_XXXXXX.Y (XXXXXX identifies the contig and Y the version of the draft) has been abbreviated as NXXXXXXX. Gene names are those reported in protein databases or have been assigned by us on the basis of the orthology relationships with mouse genes (these names are marked by an asterisk). The identification of the contig in which each of the bHLH gene is included is also given. In a few cases (marked with a question mark), we were unable to retrieve, in the genome sequence, previously cloned genes. This may be due to the fact that these genes lie in still unsequenced regions of the genome, or to some limitations of the current version of BLAST (see text for details). Chromosomal localizations are given as reported in the NCBI human genome sequence database (LocusLink and/or OMIM [77,78]).