Figure 5

Translational products from the retroviral gag-pol mRNA. In most cases, translation of the gag-pol transcript results in a Gag polyprotein including structural proteins. A translational frameshift within the p6 region allows translation beyond the p6 gag gene, resulting in a Gag-Pol fusion protein. The Gag-Pol fusion protein contains a p6^* protein, the sequence of which differs from the p6 protein as a result of the frameshift. Abbreviations: MA, p17 matrix protein; CA, p24 capsid protein; NC, p7 nucleocapsid protein; PR, protease; RT, reverse transcriptase; IN, integrase.