Cell-cycle regulation

Table 1 Cell-cycle regulatory proteins mentioned in this article

Name of protein	Names of homologs	Enzymatic function	Cell-cycle function
Bfa1		GTPase-activating protein	Mitotic exit
Bub2			Checkpoint component
BubR1			Spindle-assembly checkpoint component
Bub3			Spindle-assembly checkpoint component
Cdc20			Activator of the anaphase-promoting complex (APC)
Cdc25		Phosphatase	Activates cyclin-dependent kinase (Cdc2)
Cdc5		Polo-like protein kinase	Mitotic exit
Cdh1			Activator of the anaphase-promoting complex (APC)
Centriolin			Centrosome component
Chk1		Protein kinase	Checkpoint component
Emi1			Inhibitor of the anaphase-promoting complex (APC)
Ipl1		Aurora-like protein kinase	Spindle-assembly checkpoint component
Kendrin	Pericentrin^*		Centrosome component
Mad2			Checkpoint component
Mik1		Protein kinase	Inactivates cyclin-dependent kinase (Cdc2)
Mps1		Protein kinase	Spindle-assembly checkpoint component
Rad24	14-3-3		DNA-damage checkpoint component
Skp1			Component of a ubiquitin ligase complex, the SCF
Tem1		Ras-related GTPase	Mitotic exit
γ tubulin			Centrosome component
Wee1		Protein kinase	Inactivates cyclin-dependent kinase (Cdc2)

ISSN: 1474-760X