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Table 3 Phenotypes for which QTLs have been generated using strains that have whole genome draft sequence available

From: In silicodiscovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases

  Phenotype Number of QTLs (B6xD2)
1 Alcohol drinking - preference 7
2 Alcohol drinking - acceptance 1
3 Alcohol conditioned taste aversion 3
4 Cocaine seizures 3
5 Morphine preference 1
6 Morphine analgesia 2
7 Screen test sensitivity 8
8 Ethanol-induced locomotor activity 3
9 Basal activity 1
11 Acute alcohol withdrawal 5
12 Acute pentobarbital withdrawal 3
13 Chronic alcohol withdrawal 3
14 LORR duration 4*
15 LORR Bec 14*
16 Free-choice ethanol consumption 6*
17 Behavioral effect of stress 7*
18 Porphyria 3
19 Liver injury and porphyria 3
20 Lymphocyte proportion B220 (%) 2
21 Lymphocyte proportion CD4 (%) 1
22 Lymphocyte proportion CD8 (%) 1
23 Hepatic lipid peroxidation potential 1
24 Peak bone mass 16*
25 Variation in TRBV4 expansion 2
26 Maximal electroshock seizure threshold 4
27 Variation in cerebellar size 4
28 Variation in IGL volume 1
29 Susceptibility to mycobacterium tuberculosis 2, 1
30 Acute behavioral sensitivity to paraoxon 6*
31 Circadian period of locomotor activity 1
32 Short-term intake of saccharin 1
33 Short-term intake of sucrose 1
34 Short-term intake of quinine 1
35 Testicular weight 1
36 Bone density 6
37 Contextual fear conditioning 5
38 Hypothermic sensitivity to quinpirole 1
39 Tolerance to quinpirole 1
40 Sensitivity and tolerance to quinpirole-induced hypothermia 1
41 Baseline locomoter activity 3
42 Locomotor sensitivity to quinpirole 1
43 Hypnotic sensitivity to ethanol 1*, 1
44 Body weight 1
45 Tail length 1
46 Methamphetamine responses  
     Chewing 5
     Climbing 14
     Home cage locomotor activity 20
     Body temperature change 22
47 Pcp-induced behavior 3*
48 Amp-induced behavior 6*
49 Antinociceptive responsiveness to N2O 7
50 Corticosterone response to ethanol 5
51 High-affinity choline uptake 1
  Phenotype Number of QTLs (B6xA/J)
52 Cocaine-induced locomotor activity 2
53 Seizure susceptibility (beta-CCM administration) 3
54 Habituated open field behavior 2, 5
55 Hormone-induced ovulation rate 2, 5
56 Light-to-dark transition behavior 3, 5
57 Center time behavior 5
58 Initial ambulation in the open field 1, 4
59 Vertical rearings 1, 2
60 Trypanosomosis resistance 1
61 Nickel-induced acute lung injury 1, 2
62 PKC-alpha content 1
63 PKC activity 1
  Total number of QTLs 276
  1. *QTLs identified as suggestive in the original publications. QTLs identified as provisional in the original publications.