Skip to main content

Table 2 Misregulated genes located in regions of frequent cytogenetic aberrations

From: Identification of frequent cytogenetic aberrations in hepatocellular carcinoma using gene-expression microarray data

Ensembl ID*

Locus

Name

Fold change†

ENST00000271452

1q:165

Hypothetical protein NUF2R

10.4

ENST00000243893

20q:44

Ubiquitin-conjugating enzyme E2C

8.5

ENST00000216918

20q:30

Chromosome 20 open reading frame 1

7.2

ENST00000257535

5q:160

Pituitary tumor-transforming 1

6.7

ENST00000171466

1q:209

HSPC150 protein similar to ubiquitin-conjugating enzyme

5.6

ENST00000287395

8q:122

PRO2000 protein

4.7

ENST00000256686

12q:49

Hypothetical protein MGC5576

4.6

ENST00000229922

6p:18

Adenylyl cyclase-associated protein 2

4.6

ENST00000289943

1q:163

Ribonucleotide reductase M2 polypeptide

4.5

ENST00000271474

1q:165

Regulator of G-protein signalling 5

4.1

ENST00000230056

6p:22

Geminin

3.7

ENST00000263041

6p:56

Glutathione S-transferase A4

3.5

ENST00000245561

1q:156

Chromosome 1 open reading frame 2

3.4

ENST00000280896

4q:98

Alcohol dehydrogenase 4 (class II), pi polypeptide

-42

ENST00000245182

16q:57

Metallothionein 1L

-33

ENST00000225383

17q:64

RNA helicase-related protein

-25

ENST00000257600

12q:105

deltex (Drosophila) homolog 1

-16.9

ENST00000239938

5q:140

Early growth response 1

-10

ENST00000271629

1q:152

Extracellular matrix protein 1

-9.6

ENST00000292494

8q:142

Lymphocyte antigen 6 complex, locus E

-9.4

ENST00000283088

8p:1

KIAA0711 gene product

-7.7

ENST00000250080

17p:8

Sex hormone-binding globulin

-7

ENST00000266671

12q:76

Pleckstrin homology-like domain, family A, member 1

-7

ENST00000264005

16q:68

Lecithin-cholesterol acyltransferase

-6.7

ENST00000280188

4q:175

Glycoprotein M6A

-6.6

ENST00000262767

17q:80

Baculoviral IAP repeat-containing 5 (survivin)

-6.6

ENST00000225831

17q:32

Small inducible cytokine A2

-5.9

ENST00000257290

4q:55

Platelet-derived growth factor receptor, alpha polypeptide

-5.2

ENST00000273912

4q:83

Hypothetical protein

-5.2

ENST00000219302

16q:2

Non-metastatic cells 3, protein expressed in

-5

ENST00000255389

17q:22

Phosphatidylethanolamine N-methyltransferase

-4.9

ENST00000218564

13q:95

Dopachrome tautomerase

-4.8

ENST00000219163

16q:20

KIAA1504 protein

-3.7

ENST00000253557

17q:31

Cyclin-dependent kinase 5, regulatory subunit 1 (p35)

-3.6

  1. *Genes whose expression changed at least twofold in 70% of tumor samples in the same relative direction as the cytogenetic change and are located in regions identified as cytogenetically abnomal by CGMA in at least 35% of samples. †Fold difference in tumor tissue gene expression relative to non-cancerous tissue.