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Figure 2 | Genome Biology

Figure 2

From: Viruses in and out

Figure 2

A model of the dimerization of Rous sarcoma virus Gag protein, as proposed by Volker Vogt. Only two domains of Gag are shown (nucleocapsid, NC andcapsid, CA). Upon binding to a nucleic acid, two adjacent Gag protein molecules undergo a conformational change, which exposes a surface that can mediate dimer-dimer interaction. The Gag dimers are used as building blocks for assembly of the virus particle. Adapted with permission from Ma YM, Vogt VM: J Virol 2002, 76:5452-5462.

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