Figure 2From: Viruses in and outA model of the dimerization of Rous sarcoma virus Gag protein, as proposed by Volker Vogt. Only two domains of Gag are shown (nucleocapsid, NC andcapsid, CA). Upon binding to a nucleic acid, two adjacent Gag protein molecules undergo a conformational change, which exposes a surface that can mediate dimer-dimer interaction. The Gag dimers are used as building blocks for assembly of the virus particle. Adapted with permission from Ma YM, Vogt VM: J Virol 2002, 76:5452-5462.Back to article page