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Table 2 Mouse and human granzymes grouped according to their chromosomal localization

From: Granzymes: a family of lymphocyte granule serine proteases

Chromosomal localization

Species

Granzyme(s)

The 'tryptase' locus

  

   5q11-q12

Human

A and tryptase-2

   13D

Mouse

A

The 'chymase' locus

  

   14q11-q12

Human

B and H

   14D

Mouse

B,C,D*,E,F and G*

The 'Met-ase' locus

  

   19p13.3

Human

M

   10q21.2

Mouse

M

  1. *Granzymes D and G have not been definitively mapped, but are highly homologous to granzymes E and B, respectively.