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Table 2 Ratios of across- to within-array coefficients of variation (CVs)

From: Evaluation of normalization procedures for oligonucleotide array data based on spiked cRNA controls

Metric

Transcript

 

K10B3.8

K11C4.5

M03F4.2

AD

2.9

4.2

3.6

ADs

6.4

3.2

6.1

F

2.8

3.0

2.7

Fs

1.3

1.6

1.5

  1. Ratios of across- to within-array CVs. Across-array and within-array CVs were computed for three worm transcripts. The ratio of across-array to within-array CV is shown. Across-array CV was computed from measurements of the same probe set across three different worm array designs (A, B and C). Within-array CV was computed from serial measurements of the same probe set within the same array design. Ratios for the Fs metric are closer to 1 than those for the ADs metric, indicating that measurements of the same transcript on different array designs were more reproducible in the Fs metric than the ADs metric.