Skip to main content
Figure 5 | Genome Biology

Figure 5

From: Quod erat demonstrandum?The mystery of experimental validation of apparently erroneous computational analyses of protein sequences

Figure 5

Multiple alignment of the uncharacterized archaeal protein family that includes the alleged archaeal thymidylate synthase, MJ0757. The scheme for displaying multiple alignments is as described in the legend to Figure 1. Residues are colored at 100% consensus. In addition, metal-chelating residues in an inserted module shared by orthologs of MJ0757 are shaded blue. The asterisks denote residues in MJ0757 that were predicted to be conserved between MJ0757 and TS. Also shown are predicted secondary structures for the MJ0757 family that were obtained by using the PHD program, and the TS-like secondary structure predicted for MJ0757 in [25]. Af, A. fulgidus; Mj, M. jannaschii; Mth, M. thermoautotrophicum.

Back to article page