Figure 2

Multiple alignment of predicted archaeal dihydropteroate synthases. The scheme for displaying multiple alignments is as described in the legend to Figure 1. The consensus secondary structure was derived from the crystal structures of the Staphylococcus aureus, Mycobacterium tuberculosis and Escherichia coli DHPS (Protein Data Bank ID: 1AD1, EYE, 1AJ0). Residues are colored at 90% consensus. Af, Archaeoglobus fulgidus;Ape, Aeropyrum pernix; At, Arabidopsis thaliana; Ec, Escherichia coli; Mj, Methanococcus jannaschii;Mt, Mycobacterium tuberculosis; Mth, Methanobacterium thermoautotrophicum; Sa, Staphylococcus aureus; Sc, Saccharomyces cerevisiae; Pab, Pyrococcus abyssi.