Identification of homology in human and mouse genomes
- Kathryn Evans
© BioMed Central Ltd 2000
Received: 6 March 2000
Published: 27 April 2000
The NCBI human/mouse homology map compares the position of genes and other loci in homologous segments of DNA from human and mouse sources.
The NCBI human/mouse homology map compares the position of genes and other loci in homologous segments of DNA from human and mouse sources. The information is sorted by position for both genomes. As noted on the site, there is no detailed information available for about half the genes in the database, so much of the map should be interpreted as a reflection of probable, not confirmed, homology relationships.
Navigation is very straightforward: select the chromosome of interest, from either the mouse or human, and scroll down the page to the region of interest.
The site was last updated on 2 August 1999.
Some sort of graphical display (for example, in the form of colored bars) to indicate different levels of reliability of the described homology relationships would be useful.
A gene map of the human genome gives details of the map position of known human transcripts. The Cooperative Human Linkage Center website has further genetic mapping information for human chromosomes. A similar resource is the Mouse Genome Database (MGD) hosted by the Mouse genome informatics website.